科研队伍
姜恺

 

 最后学位:理学博士(PhD,中国科学技术大学)

 职称职务:教授、博导

 专业方向:细胞生物学、生物化学、生物物理学

 研究方向:细胞骨架与细胞周期

 电话号码:027-68758602

 电子邮件:jiangkai@whu.edu.cn

 

文化经历

1999-2003 中国科学技术大学  学士

2003-2009 中国科学技术大学  博士

 

工作经历与任职

2009-2010 荷兰伊拉斯谟医学中心(Erasmus Medical Center) 博士后

2011-2017 荷兰乌特勒支大学(Utrecht University) 博士后

2017-至今 澳门百老汇4001登录网站  教授

 

代表性论文

1. Jiang, K.*#, Rezabkova, L.*, Hua, S., Liu, Q., Capitani, G., Altelaar, A.F.M., Heck, A.J.R., Kammerer, R.A.#, Steinmetz, M.O.#, and Akhmanova, A.# (2017). Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex. Nat Cell Biol 19, 480-492. (*Co-first author, #Co-corresponding author)

2. Atherton, J.*, Jiang, K.*, Stangier, M.M., Luo, Y., Hua, S., Houben, K., van Hooff, J.J.E., Joseph, A.P., Scarabelli, G., Grant, B.J., Roberts, A.J., Topf, M., Steinmetz, M.O., Baldus, M., Moores, C.A., and Akhmanova, A. (2017). A structural model for microtubule minus-end recognition and protection by CAMSAP proteins. Nat Struct Mol Biol 24, 931-943.

3. Jiang, K., Hua, S., Mohan, R., Grigoriev, I., Yau, K.W., Liu, Q., Katrukha, E.A., Altelaar, A.F., Heck, A.J., Hoogenraad, C.C., and Akhmanova, A. (2014). Microtubule minus-end stabilization by polymerization-driven CAMSAP deposition. Dev Cell 28, 295-309.

4. Jiang, K., Toedt, G., Montenegro Gouveia, S., Davey, N.E., Hua, S., van der Vaart, B., Grigoriev, I., Larsen, J., Pedersen, L.B., Bezstarosti, K., Lince-Faria, M., Demmers, J., Steinmetz, M.O., Gibson, T.J., and Akhmanova, A. (2012). A Proteome-wide screen for mammalian SxIP motif-containing microtubule plus-end tracking proteins. Curr Biol 22, 1800-1807.

5. Faltova, L.*, Jiang, K.*, Frey, D., Wu, Y., Capitani, G., Prota, A.E., Akhmanova, A., Steinmetz, M.O., and Kammerer, R.A. (2019). Crystal Structure of a Heterotetrameric Katanin p60:p80 Complex. Structure 27, 1375-1383 e1373.

6. Jiang, K.*, Faltova, L.*, Hua, S., Capitani, G., Prota, A.E., Landgraf, C., Volkmer, R., Kammerer, R.A., Steinmetz, M.O., and Akhmanova, A. (2018). Structural Basis of Formation of the Microtubule Minus-End-Regulating CAMSAP-Katanin Complex. Structure 26, 375-382 e374.

7. Jiang, K., Wang, J., Liu, J., Ward, T., Wordeman, L., Davidson, A., Wang, F., and Yao, X. (2009). TIP150 interacts with and targets MCAK at the microtubule plus ends. EMBO Rep 10, 857-865.

8. Jiang, K., and Akhmanova, A. (2011). Microtubule tip-interacting proteins: a view from both ends. Curr Opin Cell Biol 23, 94-101.


 

 

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