科学研究
Adding to the STING
编辑:www.4001.com  发布时间:2014-12-18  来源:  阅读次数:
Immunity.2014 Dec 18;41(6):871-3. doi: 10.1016/j.immuni.2014.12.002.

Addingto theSTING.

Shu HB 1, Wang YY 2.

Author information

Abstract

STING(also known as MITA) is a central component in innate immunity against DNA virus. In this issue of Immunity, Wang et al. (2014) demonstrate that K27-linked polyubiquitination ofSTING(MITA) by the ER-associated E3 ligase AMFR is essential forSTING(MITA)-mediated signaling and innate antiviral response.

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